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Dec 8 - Pfizer says 3 doses offers significant protection against omicron



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 2 months ago '20        #1
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Dec 8 - Pfizer says 3 doses offers significant protection against omicron
 

 
Pfizer and BioNTech said Wednesday that laboratory tests suggest that three doses of their coronavirus vaccine offer significant protection against the fast-spreading Omicron variant of the virus.

The companies said that tests of blood from individuals who received only two doses found more than a 25-fold reduction in antibody levels against the Omicron variant compared to an earlier version of the virus. That finding indicates that two doses alone “may not be sufficient to protect against infection” by the new variant, the companies said.

But the blood samples obtained from people one month after they had received a booster shot showed neutralizing antibodies against the Omicron variant comparable to the levels of antibodies against a previous version of the virus after two doses, the companies said in a statement.

At the same time, the tests suggested that the mutations in Omicron do not appear to significantly affect T cells — another critical part of the immune system’s response. That suggests “vaccinated individuals may still be protected against severe forms of the disease” after only two doses, the companies said.

These experiments, done on cells and antibodies in the lab, cannot say for sure how the vaccines will perform in the real world. Vaccines stimulate a wide-ranging immune response that involves more than just antibodies. So these experiments offer an incomplete picture of how well the vaccine protects against hospitalization or death from Omicron.

But the results seem to underscore the importance of booster shots in combating the new variant.

“Our preliminary, first data set indicate that a third dose could still offer a sufficient level of protection from disease of any severity caused by the Omicron variant,” said Dr. Ugur Sahin, the chief executive officer of BioNTech, Pfizer’s German partner.

The results come one day after a preliminary report on laboratory experiments in South Africa found Omicron seemed to dull the power of Pfizer’s vaccine. Those experiments also hinted that people who have received a booster shot might be better protected.

The Omicron variant has now spread to dozens of countries, and while the Delta variant is still overwhelmingly dominant in the United States, the Biden administration is bracing for Omicron’s impact.

In an interview last week, Dr. Albert Bourla, Pfizer’s chairman and chief executive officer, said the company began developing a version of its vaccine specifically targeting Omicron on the day after Thanksgiving. Moderna is on the same path.

If a different version of the vaccine turns out to be needed, Dr. Bourla said, Pfizer could produce it within 95 days.

“We will be able to switch overnight production,” he said. “There’s not going to be a need to start producing new machinery, new equipment, new formulations.” He added: “We will be able to produce nearly the same number of doses as our current vaccine.”

He said that since the Pfizer-BioNTech vaccine first emerged, Pfizer has developed two other prototypes in response to new variants. Neither proved necessary, he said, because the original vaccine worked against the virus’s mutations.

At a White House briefing Tuesday, Dr. Anthony S. Fauci, the government’s top infectious disease expert, said it would still be weeks before scientists understand how virulent the Omicron variant is.

“We shouldn’t be making any definitive conclusions, certainly not before the next couple of weeks,” he said.

He said early reports from South African medical officials presented a somewhat hopeful picture of Omicron’s impact. Researchers at a major hospital complex in Pretoria reported this week that patients with the coronavirus are significantly less ill than those they have treated before, and that other hospitals are seeing the same trends.

“We are not seeing a very severe profile of disease,” Dr. Fauci said, adding that hospital stays were shorter and patients required less oxygen. “It might be, and I underscore might, be less severe, as shown by the ratio of hospitalizations per number of new cases.”

He cautioned that data were preliminary and could be influenced by a higher proportion of younger people infected. He also noted that South Africa has a less vaccinated population than the United States, and a greater percentage infected with H.I.V., which can damage the immune system.

The South African study published Tuesday found that antibodies produced by vaccinated people were much less successful at keeping the Omicron variant from infecting cells than other forms of the coronavirus.

Scientists said the results were somewhat worrisome, but no cause for panic. The data suggests that vaccinated people might be vulnerable to breakthrough infections with Omicron, which is spreading rapidly in South Africa and has appeared in dozens of countries around the world.

But vaccines stimulate a wide-ranging immune response that involves more than just antibodies. So these experiments offer an incomplete picture of how well the vaccine protects against hospitalization or death from Omicron.


visit this link https://www.nytimes.com/l .. gainst-omicron
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80 comments
 

 2 months ago '16        #2
Fastrap87  topics gone triple plat - Number 1 spot x2
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+12   

 2 months ago '20        #3
God is Good 
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and then the next variant they create will be worse than omicron and you will need three more doses and two boosters in the first 90 days

+37   

 2 months ago '05        #4
pippen33 
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These Pharm companies done hit the ultimate lick with Covid
+59   

 2 months ago '21        #5
Fras 
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fu*k these pharmaceutical companies, and fu*k the vaccine.

fu*k all these Democrats mandating their products too, in turn making these fu*kers billion and trillionaires.

fu*k OFF


Last edited by Fras; 12-08-2021 at 01:21 PM..
+33   

 2 months ago '14        #6
Sense Maker  topics gone triple plat - Number 1 spot x1
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Boosted




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 2 months ago '14        #7
Sense Maker  topics gone triple plat - Number 1 spot x1
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 Fras said


fu*k these pharmaceutical companies, and fu*k the vaccine.

fu*k all these Democrats mandating their products too, in turn making this fu*kers billion and trillionaires.

fu*k OFF


Roll wit it or get rolled over chump!
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 2 months ago '20        #8
BuiltForThis  topics gone triple plat - Number 1 spot x9 OP
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 Sense Maker said


Roll wit it or get rolled over chump!
Sickly estrogen filled lab rat butt-butt logic




+10   

 2 months ago '18        #9
OLITO 
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i got the first set of vaccine but not sure that i will be getting a booster shot, for health purposes..
+3   

 2 months ago '14        #10
Sense Maker  topics gone triple plat - Number 1 spot x1
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 BuiltForThis said
Sickly estrogen filled lab rat butt-butt logic






See, at least you don't take this sh*t personally. Still an a**hole tho.
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 2 months ago '16        #11
Fastrap87  topics gone triple plat - Number 1 spot x2
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 OLITO said
i got the first set of vaccine but not sure that i will be getting a booster shot, for health purposes..
then you're a magat, antiscience, antivaxxer


take a seat





Last edited by Fastrap87; 12-08-2021 at 02:17 PM..
+12   

 2 months ago '11        #12
JetSetter22 
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Year 2035

Pfizer says the 15th booster will make u almost immune to the alphabetacappa strain of covid
+25   

 2 months ago '07        #13
iTzMe!  topics gone triple plat - Number 1 spot x1
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Is it 3 on top of the 2 I already have or 3 more for a total of 5 ?
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 2 months ago '16        #14
Fastrap87  topics gone triple plat - Number 1 spot x2
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 iTzMe! said
Is it 3 on top of the 2 I already have or 3 more for a total of 5 ?
5!
trust the $cience
+3   

 2 months ago '05        #15
pippen33 
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 iTzMe! said
Is it 3 on top of the 2 I already have or 3 more for a total of 5 ?
Your booster gonna need a booster

They gonna recommend boosters every year. There will be no end for this sh*t.
+7   

 2 months ago '18        #16
dogfood2 
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Trump 2024 confirmed at this point. Biden and his who fu*k boys k*lled America
+11   

 2 months ago '17        #17
10%er  topics gone triple plat - Number 1 spot x23
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 Fastrap87 said
These idiots still think its about health...
+11   

 2 months ago '19        #18
dmboat990 
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what’s going to happen when the next variant comes then the one after that then the sixth one most of you sheep a*s n*ggas going to be walking this bi*ch like some remote control zombies
+12   

 2 months ago '05        #19
projectd06 
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 iTzMe! said
Is it 3 on top of the 2 I already have or 3 more for a total of 5 ?
3 total.

 2 months ago '05        #20
hbk83 
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I bet it does
+2   

 2 months ago '18        #21
dakidjahsiah 
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+14   

 2 months ago '20        #22
Xiox  topics gone triple plat - Number 1 spot x1
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This will definitely make a four seasons worth while documentary we should call it The Great Heist
+1   

 2 months ago '21        #23
PureEther 
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+21   

 2 months ago '16        #24
Ghostface Killa  topics gone triple plat - Number 1 spot x1
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All the vaccine evangelists lurking and slapping because they haven't received their official statement yet.

+13   

 2 months ago '16        #25
Fastrap87  topics gone triple plat - Number 1 spot x2
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 Ghostface k*lla said
All the vaccine evangelists lurking and slapping because they haven't received their official statement yet.





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