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Apr 19 - 2 yr old boy shows signs of early puberty after using weed oil to treat epilepsy



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Apr 19 - 2 yr old boy shows signs of early puberty after using weed oil to treat epilepsy
 

 
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Changes started to occur a month after the boy’s mother began giving him cannabis oil ordered online without a prescription.

“This case demonstrates a temporal a*sociation between cannabis use and development of precocious puberty.” / PHOTO BY GETTY IMAGES
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A case study that found a two-year-old boy treated with cannabis oil for severe epilepsy showed signs of puberty indicates “more research on the effects of cannabis use on human hormonal markers and clinical outcomes is necessary.”

Investigators out of Birmingham, U.K. made clear the finding relates to one boy who used cannabis oil obtained without a prescription, according to a case report write-up. They unearthed no previous cases a*sociated with cannabinoid use and “no existing evidence investigating the effects of cannabinoids on infants.”

Even so, researchers caution that using medical cannabis to treat severe childhood epilepsy may be linked to early puberty, called precocious puberty, defined as onset of puberty before the age of nine.

Authors could not say the boy’s early puberty is a direct consequence of THC in cannabis activating the hypothalamo-pituitary-gonadal (HPG) axis that is “responsible for the development and regulation of several of the body systems, including those for reproduction.” But they maintained that “this case demonstrates a temporal a*sociation between cannabis use and development of precocious puberty.”

While cannabis oil has been found to help reduce seizures in childhood epilepsy, no consensus exists on its impact on the trio of glands, namely the HPG axis, according to BMJ Case Reports.

Doctors diagnosed early puberty in the young boy, citing testicular enlargement, increased penile length, growth of coarse body hair, change in body odour, facial and truncal acne and abnormally high levels of serum testosterone — 19 nmol/L compared to a normal level of less than 0.9 — and other reproductive hormones.

The report cites previous studies linking “cannabis use to increased levels of the male hormone, testosterone, raising the question of a possible dose-related effect as higher strength preparations are readily available.”

The boy’s mother reported the changes in her son started to occur approximately six months earlier, just a month after she began giving him cannabis oil she had ordered online without a prescription. The oil was advertised as having less than 0.4 per cent THC concentration.

The mother made the decision to order the oil after his limited response to other treatments, reporting that her son had suffered estimated 20-plus seizures each day since his birth and the frequency was increasing. After starting to use the cannabis oil, the number of daily seizures had dropped to about five daily.

Case report authors point out that most of the research exploring the effectiveness of cannabis oil for reducing epilepsy-related seizure frequency has been done in the lab. “Until a more robust evidence base is established, clinicians should be cautious of hormonal consequences of cannabis-related products, particularly as children with brain abnormalities may be more susceptible to these effects,” they write.

A study published last year notes the anti-convulsant properties of several cannabinoids, namely THC and CBD, “have been demonstrated in both in vitro and in vivo studies.” It adds that “cannabis herbal extracts appear to provide greater efficacy in decreasing seizure frequency, but the studies a*sessing cannabis herbal extract are either retrospective or small-scale observational studies.”

Another published study, also from last year states that “the burden of intractable epilepsy on infants and children and their families is enormous, and in addition to the risks carried by the actual seizures, it significantly affects the children’s development and quality of life.”

In the case of the two-year-old boy, he presented developmental delay, as seen by poor muscle tone and control, impaired vision and poor socialization.

A review from 2018, however, “found CBD to be more effective than placebo at halving seizure frequency and improving quality of life.” The 2018 review itself states that “pharmaceutical-grade CBD as adjuvant treatment in paediatric-onset, drug-resistant epilepsy may reduce seizure frequency.”

Authors of the most recent case review conclude their research “demonstrates a paradigm shift over decades as larger populations can now be studied with the increasing popularity of cannabis use.”

visit this link https://www.thegrowthop.c .. dhood-epilepsy
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42 comments
 

Top 10 most slapped recently  4 weeks ago '05        #2
ice wolf  topics gone triple plat - Number 1 spot x3 OP
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Imma be first up here with the obvious shout out
@
+18   

 4 weeks ago '19        #3
alwaysworking  topics gone triple plat - Number 1 spot x2
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Cap. She would be in jail for buying drugs illegally and shipping is a federal offense.I’m sure what she got is cbd.
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 4 weeks ago '06        #4
Bilal  topics gone triple plat - Number 1 spot x10
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What were the early puberty signs? Hair? If so you can't ame the cbd that's happened a few times it's a rare occurrence I've read a few stories about going through puberty at 2


Last edited by Bilal; 04-19-2021 at 06:12 PM..
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 4 weeks ago '12        #5
Steelgrip 
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 Bilal said
What were the early puberty signs? Hair? If so you can't ame the cbd that's happened a few times it's a rare occurrence I've read a few stories about going through puberty at 2
Doctors diagnosed early puberty in the young boy, citing testicular enlargement, increased penile length, growth of coarse body hair, change in body odour, facial and truncal acne and abnormally high levels of serum testosterone — 19 nmol/L compared to a normal level of less than 0.9 — and other reproductive hormones.

She opened his diaper one day and he had instantly reached his peak potential like Gon





he hit her with “spit on my mufu*kin balls. They should look like two disco balls in a second. Spit on em!"




+24   

 4 weeks ago '06        #6
Bilal  topics gone triple plat - Number 1 spot x10
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 Steelgrip said
She opened his diaper one day and he had reached his peak potential like Gon





he hit her with “spit on my mufu*kin balls. They should look like two disco balls in a second. Spit on em!"




Yeah don't blame cbd it's a rare disease it starts to grow your body at two you look 13 at that age.




extremely rare disease that affects only men because you have to have testicles, which is why it’s also called testotoxicosis. The condition tricks the testicles into thinking the body is ready to go through puberty — so wham, the floodgates open and the body is saturated with testosterone. The result is premature everything: bone growth, muscle development, body hair, the full menu of dramatic physical changes that accompany puberty. Only instead of being 13, you’re 2.
+6   

 4 weeks ago '18        #7
Signor  topics gone triple plat - Number 1 spot x44
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 Steelgrip said
She opened his diaper one day and he had instantly reached his peak potential like Gon





he hit her with “spit on my mufu*kin balls. They should look like two disco balls in a second. Spit on em!"






you want his mom to spit on his balls?


this so out of pocket
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 4 weeks ago '21        #8
RackboyCam 
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That sh*t really do put hair on the chest
+5   

 4 weeks ago '21        #9
JayMurdoch 
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Honestly doesn't seem so bad. It would be a good counter effect to the pussification of modern society, sounds like that kid is going to be a beast when he gets older.



+19   

 4 weeks ago '21        #10
nodayzoffatl  topics gone triple plat - Number 1 spot x3
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 RackboyCam said
That sh*t really do put hair on the chest
you spelled nuts wrong
+4   

 4 weeks ago '20        #11
Ball Man 
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This some stretch armstrong levels of reach, can't really base sh*t off of just one case...
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 4 weeks ago '16        #12
foshoVoodoo  topics gone triple plat - Number 1 spot x34
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@ them thc vapes aight bredda
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 4 weeks ago '21        #13
RackboyCam 
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 alwaysworking said
Cap. She would be in jail for buying drugs illegally and shipping is a federal offense.I’m sure what she got is cbd.
This is correct CBD is regularly prescribed to treat juvenile epilepsy there is no was a healthcare practitioner would prescribe thc to a kid
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 4 weeks ago '11        #14
Tony Franks 
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He is evolving into a Saiyan. Leave him be.
+2   

 4 weeks ago '15        #15
SmokinBigDope  topics gone triple plat - Number 1 spot x3
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Son bout to be the next bron. @ww been taking Ls all week




+6   

 4 weeks ago '05        #16
P DRILLA 
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 Steelgrip said
She opened his diaper one day and he had instantly reached his peak potential like Gon





he hit her with “spit on my mufu*kin balls. They should look like two disco balls in a second. Spit on em!"




wesley
+3   

 4 weeks ago '13        #17
The Originator 
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RIP @.
+3   

 4 weeks ago '08        #18
jmack26  topics gone triple plat - Number 1 spot x5
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IDK IF this is good or bad just reading title only
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 4 weeks ago '20        #19
MeNoSenYouNoCom  topics gone triple plat - Number 1 spot x7
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 ice wolf said
Imma be first up here with the obvious shout out
@
came in here just to make sure this was a @ thread, its not so was gon slap but you gave respect
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 4 weeks ago '20        #20
MeNoSenYouNoCom  topics gone triple plat - Number 1 spot x7
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 nodayzoffatl said
you spelled nuts wrong
+1   

 4 weeks ago '19        #21
ITL  topics gone triple plat - Number 1 spot x3
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In a related story, marijuana dispensaries have come under fire by LGBT advocates , who’ve deemed such businesses as “transphobic havens of hate”

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 4 weeks ago '15        #22
Mexicanelvis 
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fu*k weed guy was bullied by kids who hit puberty early, it explains everything
+8   

 4 weeks ago '09        #23
messy marv stan  topics gone triple plat - Number 1 spot x62
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@ already camping outside his local weed shop for a week just to buy $5000 worth of kush tomorrow
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 4 weeks ago '18        #24
Sandyy  topics gone triple plat - Number 1 spot x6
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this a good thing he going to be working a warehouse job by 10 at this puberty rate

they bout to have one of those industrial revolution 10 yr old with a full time job, drinking problem and new born
+3   

Top 10 most slapped recently  4 weeks ago '05        #25
ice wolf  topics gone triple plat - Number 1 spot x3 OP
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 messy marv stan said
@ already camping outside his local weed shop for a week just to buy $5000 worth of kush tomorrow
That's why @ hasn't commented yet. Homie greening out off that loud.
+3   



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