2,568
 

Aug 13 - Scientists can now manipulate brain cells using smartphone


 
 
1
most viewed right now
  76
38 comments @wild'ish


section   (0 bx goons and 1 bystanders) Share this on Twitter       Share this on Facebook
 

section BX Daily Bugle
  
 5 days ago '04        #1
542 page views
6 comments


Exs 535 heat pts535
space
avatar space
space
$14,928 | Props total: 36910 36910
Aug 13 - Scientists can now manipulate brain cells using smartphone
 

 
image



A team of scientists in Korea and the United States have invented a device that can control neural circuits using a tiny brain implant controlled by a smartphone.

Researchers, publishing in Nature Biomedical Engineering, believe the device can speed up efforts to uncover brain diseases such as Parkinson's, Alzheimer's, addiction, depression, and pain.

The device, using Lego-like replaceable drug cartridges and powerful bluetooth low-energy, can target specific neurons of interest using drug and light for prolonged periods.

"The wireless neural device enables chronic chemical and optical neuromodulation that has never been achieved before," said lead author Raza Qazi, a researcher with the Korea Advanced Institute of Science and Technology (KAIST) and University of Colorado Boulder.

Qazi said this technology significantly overshadows conventional methods used by neuroscientists, which usually involve rigid metal tubes and optical fibers to deliver drugs and light. Apart from limiting the subject's movement due to the physical connections with bulky equipment, their relatively rigid structure causes lesion in soft brain tissue over time, therefore making them not suitable for long-term implantation. Though some efforts have been put to partly mitigate adverse tissue response by incorporating soft probes and wireless platforms, the previous solutions were limited by their inability to deliver drugs for long periods of time as well as their bulky and complex control setups.

To achieve chronic wireless drug delivery, scientists had to solve the critical challenge of exhaustion and evaporation of drugs. Researchers from the Korea Advanced Institute of Science and Technology and the University of Washington in Seattle collaborated to invent a neural device with a replaceable drug cartridge, which could allow neuroscientists to study the same brain circuits for several months without worrying about running out of drugs.

These 'plug-n-play' drug cartridges were a*sembled into a brain implant for mice with a soft and ultrathin probe (thickness of a human hair), which consisted of microfluidic channels and tiny LEDs (smaller than a grain of salt), for unlimited drug doses and light delivery.

Controlled with an elegant and simple user interface on a smartphone, neuroscientists can easily trigger any specific combination or precise sequencing of light and drug deliveries in any implanted target animal without need to be physically inside the laboratory. Using these wireless neural devices, researchers could also easily setup fully automated animal studies where behaviour of one animal could positively or negatively affect behaviour in other animals by conditional triggering of light and/or drug delivery.

"This revolutionary device is the fruit of advanced electronics design and powerful micro and nanoscale engineering," said Jae-Woong Jeong, a professor of electrical engineering at KAIST. "We are interested in further developing this technology to make a brain implant for clinical applications."

Michael Bruchas, a professor of anesthesiology and pain medicine and pharmacology at the University of Washington School of Medicine, said this technology will help researchers in many ways.

"It allows us to better dissect the neural circuit basis of behaviour, and how specific neuromodulators in the brain tune behaviour in various ways," he said. "We are also eager to use the device for complex pharmacological studies, which could help us develop new therapeutics for pain, addiction, and emotional disorders."

The researchers at the Jeong group at KAIST develop soft electronics for wearable and implantable devices, and the neuroscientists at the Bruchas lab at the University of Washington study brain circuits that control stress, depression, addiction, pain and other neuropsychiatric disorders. This global collaborative effort among engineers and neuroscientists over a period of three consecutive years and tens of design iterations led to the successful validation of this powerful brain implant in freely moving mice, which researchers believe can truly speed up the uncovering of brain and its diseases.

This work was supported by grants from the National Research Foundation of Korea, U.S. National Institute of Health, National Institute on Drug Abuse, and Mallinckrodt Professorship.

visit this link https://www.sciencedaily. .. 0805143525.htm
+5   



best
worst
6 comments
 

 4 days ago '10        #2
Trilluminati GA 435 heat pts435
space
avatar space
space
$52,089 | Props total: 18195 18195
Nwo sh*t
+1   

 4 days ago '15        #3
ThatGuy247 
space
avatar space
space
$743 | Props total: 1431 1431
If they're telling us about it now. it's been in use at least a decade.......
+10   

 4 days ago '17        #4
Lazy 4 heat pts
space
space
space
$2,819 | Props total: 9714 9714
 ThatGuy247 said
If they're telling us about it now. it's been in use at least a decade.......
It's how hearing implants work with those with severe auditory issues

This tech is older than most Boxden users
+2   

 4 days ago '04        #5
Exs 535 heat pts535 OP
space
avatar space
space
$14,928 | Props total: 36910 36910
first responders are strong in this one

Top 10 most slapped recently  4 days ago '05        #6
Daddy Black 2 heat pts
space
avatar space
space
$9,818 | Props total: 7483 7483
I saw this on the news last month. They actually successfully stopped the shaking from Parkinson’s using this device. sh*t is crazy.
+2   

 4 days ago '12        #7
acefresh 24 heat pts24
space
avatar space
space
$10,274 | Props total: 37523 37523
The next 10 years is going to be very interesting.
+2   





 


Join bx
 
 

yesterday...


most viewed right now
online now  26
Aug 16 - Jeffrey Epstein spent hours alone with mysterious woman in lockup
22 comments
1 day ago
@news
most viewed right now
online now  25
Video inside Tariq Nasheed gives Jay z his butter biscuits
98 comments
2 days ago
@hiphop
most viewed right now
+59online now  18
Video inside Producer Bryan Michael Cox "Jay-Z Told Jermaine Dupri Not To Work With ..
141 comments
2 days ago
@hiphop
most viewed right now
online now  8
Do You Believe In Ghost? Ever Had a Ghostly Experience?
110 comments
1 day ago
@wild'ish
back to top
register contact Follow BX @ Twitter Follow BX @ Facebook search BX privacy