The difference between CBD and THC:
You already know this if you've ever smoked weed, but "the major difference between the two compounds is that CBD is a non-intoxicating compound that will not leave you feeling high. THC, on the other hand, does have intoxicating and euphoric effects, especially when it’s taken in higher doses," Dr. Axe explains.
Here's how it works:
According to Dr. Axe, "Both CBD and THC are found in the ancient plant Cannabis sativa, and both interact with receptors in the Endocannabinoid System, a biochemical communication system that was only discovered about 25 years ago. Overall, this system works to keep the body in homeostasis.
"CBD interacts with cannabinoid receptors (called CB1 and CB2) throughout the body, including the central nervous system and immune system. These receptors influence the body’s ability to function properly by producing effects within our cells."
In other words, CBD seems to be very important and effective at maintaining balance between interdependent elements in the body and acts as a mediator when things start to go haywire.
For example, a study found that CBD is extremely effective at balancing and lowering the stress hormone cortisol. This is important—we all know how toxic stress can be.
Finding the perfect dose:
Something to keep in mind is that unlike pharmaceuticals, there hasn’t been enough clinical research on CBD to fully determine exact dosing guidelines.
Dr. Axe says, "There’s no official serving size for CBD. Everyone is different, with some people being more sensitive than others.
"You’ll typically want to start with a lower dose of 5-10 milligrams, or what your healthcare professional suggests. Give your starting dose 5-7 days and track whether or not they meet your original goals. If you haven’t noticed steps towards meeting your goals, try increasing your dose by about 5 milligrams and try that for another 5-7 days."
What to avoid:
CBD might interfere with certain routinely prescribed drugs, so it's always best to check with your doctor before adding it to your daily routine.
"CBD is a potent inhibitor of CYP450 enzymes, which work to metabolize prescription drugs and eliminate toxins from the body. This means that using CBD while taking prescription medications may alter the body’s ability to metabolize or break down the drug."
Ultimately Dr. Axe recommends steering clear of mixing those prescriptions with CBD as they may have adverse interactions. "Any medication that’s metabolized by CYP450 enzymes shouldn’t be taken with CBD."
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